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This paper aims to analyze the effects of harmful biotic and abiotic factors on coniferous and broadleaved stands grown in different ecosite classes of forest district Chlumská hora, which belongs to the management-plan area Forestry Technical School Žlutice, in the period of 2003 – 2010. The study confirmed the influence of habitat on growing wood species, especially common spruce monocultures. The greatest damage was found in Norway spruce stands, grown on inappropriate sites. Growing woods in unsuitable environmental conditions affects their state of health and creates a predisposition for harmful effects of biotic and abiotic factors. The most serious abiotic factor in investigated locality is wind. The most serious insect pest of Norway spruce is eight-toothed spruce bark Ips typographus L., whose development is also conditioned by the weakening of the primary host species. There is a greater possibility of outbreak in monocultures. Great damage to forest stands is caused by parasitic wood-destroying fungi especially by Armillaria ostoyae (Romagn.) Herink which infect living trees due to their physiological weakness.